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1

Mécanismes moléculaires et cellulaires de l'action de l'insuline. Application à la physiologie et à la pathologie

Jacqueline Capeau, Christèle Desbois-Mouthon, Jocelyne Magré, Martine Caron, Corinne Vigouroux, Olivier Lascols, Gisèle Cherqui

Journal:

Nutrition Clinique et Métabolisme

Year:

1996

File:

PDF, 1.50 MB

1996

2

Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells

Marie-José Blivet-Van Eggelpoël, Hamza Chettouh, Laetitia Fartoux, Lynda Aoudjehane, Véronique Barbu, Colette Rey, Sabrina Priam, Chantal Housset, Olivier Rosmorduc, Christèle Desbois-Mouthon

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 1.08 MB

english, 2012

3

Dysregulation of glycogen synthase kinase-3β signaling in hepatocellular carcinoma cells

Christèle Desbois-Mouthon, Marie-José Blivet-Van Eggelpoë, Eléonore Beurel, Mathieu Boissan, Roland Delélo, Axelle Cadoret, Jacqueline Capeau

Journal:

Year:

2002

Language:

english

File:

PDF, 1.03 MB

english, 2002

4

Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis

Eduardo Schiffer, Chantal Housset, Wulfran Cacheux, Dominique Wendum, Christèle Desbois-Mouthon, Colette Rey, François Clergue, Raoul Poupon, Véronique Barbu, Olivier Rosmorduc

Journal:

Year:

2005

Language:

english

File:

PDF, 333 KB

english, 2005

5

c-myc-induced hepatocarcinogenesis in the absence of IGF-I receptor

Axelle Cadoret, Christèle Desbois-Mouthon, Dominique Wendum, Patricia Leneuve, Christine Perret, François Tronche, Chantal Housset, Martin Holzenberger

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

6

Impact of IGF-1R/EGFR cross-talks on hepatoma cell sensitivity to gefitinib

Christèle Desbois-Mouthon, Wulfran Cacheux, Marie-José Blivet-Van Eggelpoël, Véronique Barbu, Laetitia Fartoux, Raoul Poupon, Chantal Housset, Olivier Rosmorduc

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 598 KB

english, 2006

7

Insulin and IGF-1 stimulate the β-catenin pathway through two signalling cascades involving GSK-3β inhibition and Ras activation

Desbois-Mouthon, Christèle, Cadoret, Axelle, Blivet-Van Eggelpoël, Marie-José, Bertrand, France, Cherqui, Gisèle, Perret, Christine, Capeau, Jacqueline

Journal:

Year:

2001

Language:

english

File:

PDF, 232 KB

english, 2001

8

Glycogen synthase kinase-3 inhibitors augment TRAIL-induced apoptotic death in human hepatoma cells

Eléonore Beurel, Marie-José Blivet-Van Eggelpoël, Michel Kornprobst, Sylviane Moritz, Roland Delelo, François Paye, Chantal Housset, Christèle Desbois-Mouthon

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1.04 MB

english, 2009

9

Thérapie anti-EGFR: vers un ciblage « à la carte » du carcinome hépatocellulaire

Lætitia Fartoux, Christèle Desbois-Mouthon, Raoul Poupon, Olivier Rosmorduc

Journal:

Gastroentérologie Clinique et Biologique

Year:

2006

Language:

french

File:

PDF, 467 KB

french, 2006

10

Insulin Differentially Regulates SAPKs/JNKs and ERKs in CHO Cells Overexpressing Human Insulin Receptors

Christèle Desbois-Mouthon, Marie-José Blivet-Van Eggelpoel, Martine Auclair, Gisèle Cherqui, Jacqueline Capeau, Martine Caron

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 346 KB

english, 1998

11

Targeting STAT3 in hepatocellular carcinoma: Sorafenib again…

Olivier Rosmorduc, Christèle Desbois-Mouthon

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 470 KB

english, 2011

12

Overexpression of Insulin Receptor Substrate-2 in Human and Murine Hepatocellular Carcinoma

Mathieu Boissan, Eléonore Beurel, Dominique Wendum, Colette Rey, Yann Lécluse, Chantal Housset, Marie-Lise Lacombe, Christèle Desbois-Mouthon

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 1.01 MB

english, 2005

13

Severe resistance to insulin and insulin-like growth factor-I in cells from a patient with leprechaunism as a result of two mutations in the tyrosine kinase domain of the insulin receptor

Christèle Desbois-Mouthon, Claude Danan, Serge Amselem, Marie-José Blivet-Van Eggelpoel, Caroline Sert-Langeron, Michel Goossens, Claude Besmond, Jacqueline Capeau, Martine Caron

Journal:

Year:

1996

Language:

english

File:

PDF, 1.04 MB

english, 1996

14

GSK-3β inhibition by lithium confers resistance to chemotherapy-induced apoptosis through the repression of CD95 (Fas/APO-1) expression

Eléonore Beurel, Michel Kornprobst, Marie-José Blivet-Van Eggelpoël, Carmen Ruiz-Ruiz, Axelle Cadoret, Jacqueline Capeau, Christèle Desbois-Mouthon

Journal:

Experimental Cell Research

Year:

2004

Language:

english

File:

PDF, 459 KB

english, 2004

15

Dysregulation of glycogen synthase kinase-3β signaling in hepatocellular carcinoma cells

Christèle Desbois-Mouthon, Marie-José Blivet-Van Eggelpoël, Eléonore Beurel, Mathieu Boissan, Roland Delélo, Axelle Cadoret, Jacqueline Capeau

Journal:

Year:

2002

Language:

english

File:

PDF, 287 KB

english, 2002

16

Mitogen-activated protein kinase-activated protein kinase 2 mediates resistance to Hydrogen peroxide-induced oxidative stress in Human hepatobiliary Cancer cells

Ho-Bouldoires, Thanh Huong Nguyen, Clapéron, Audrey, Mergey, Martine, Wendum, Dominique, Desbois-Mouthon, Christèle, Tahraoui, Sylvana, Fartoux, Laetitia, Chettouh, Hamza, Merabtene, Fatiha, Scatton,

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

17

Antiinsulin Receptor Autoantibodies Induce Insulin Receptors to Constitutively Associate with Insulin Receptor Substrate-1 and -2 and Cause Severe Cell Resistance to Both Insulin and Insulin-Like Growth Factor I 1

Auclair, Martine, Vigouroux, Corinne, Desbois-Mouthon, Christèle, Deibener, Joëlle, Kaminski, Pierre, Lascols, Olivier, Cherqui, Gisèle, Capeau, Jacqueline, Caron, Martine

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1999

Language:

english

File:

PDF, 1.24 MB

english, 1999

18

Insulin-Mediated Cell Proliferation and Survival Involve Inhibition of c-Jun N-terminal Kinases through a Phosphatidylinositol 3-Kinase- and Mitogen-Activated Protein Kinase Phosphatase-1-Dependent Pathway 1

Desbois-Mouthon, Christele, Cadoret, Axelle, Blivet-Van Eggelpoël, Marie-Jose, Bertrand, France, Caron, Martine, Atfi, Azeddine, Cherqui, Gisele, Capeau, Jacqueline

Journal:

Year:

2000

Language:

english

File:

PDF, 1.35 MB

english, 2000

19

GSK-3β reactivation with LY294002 sensitizes hepatoma cells to chemotherapy-induced apoptosis

Beurel, Eléonore, Kornprobst, Michel, Blivet-Van Eggelpoël, Marie-José, Cadoret, Axelle, Capeau, Jacqueline, Desbois-Mouthon, Christele

Journal:

International Journal of Oncology

Year:

2005

Language:

english

File:

PDF, 2.19 MB

english, 2005

20

Hepatic myofibroblasts promote the progression of human cholangiocarcinoma through activation of epidermal growth factor receptor

Clapéron, Audrey, Mergey, Martine, Aoudjehane, Lynda, Ho-Bouldoires, Thanh Huong Nguyen, Wendum, Dominique, Prignon, Aurélie, Merabtene, Fatiha, Firrincieli, Delphine, Desbois-Mouthon, Christèle, Scat

Journal:

Year:

2013

Language:

english

File:

PDF, 1.32 MB

english, 2013

21

Hyperinsulinaemia and insulin signalling in the pathogenesis and the clinical course of hepatocellular carcinoma

Chettouh, Hamza, Lequoy, Marie, Fartoux, Laetitia, Vigouroux, Corinne, Desbois-Mouthon, Christèle

Journal:

Liver International

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

22

Somatostatin receptors in resected hepatocellular carcinoma: status and correlation with markers of poor prognosis

Lequoy, Marie, Desbois-Mouthon, Christèle, Wendum, Dominique, Gupta, Vandana, Blachon, Jean-Luc, Scatton, Olivier, Dumont, Sylvie, Bonnemaire, Mireille, Schmidlin, Fabien, Rosmorduc, Olivier, Fartoux,

Journal:

Year:

2016

Language:

english

File:

PDF, 319 KB

english, 2016

23

The beta secretase BACE1 regulates the expression of insulin receptor in the liver

Meakin, Paul J., Mezzapesa, Anna, Benabou, Eva, Haas, Mary E., Bonardo, Bernadette, Grino, Michel, Brunel, Jean-Michel, Desbois-Mouthon, Christèle, Biddinger, Sudha B., Govers, Roland, Ashford, Michae

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.66 MB

english, 2018

24

IGF2/IR/IGF1R pathway in tumor cells and myofibroblasts mediates resistance to EGFR inhibition in cholangiocarcinoma

Vaquero, Javier, Lobe, Cindy, Tahraoui, Sylvana, Clapéron, Audrey, Mergey, Martine, Merabtene, Fatiha, Wendum, Dominique, Coulouarn, Cédric, Housset, Chantal, Desbois-Mouthon, Christèle, Praz, Francoi

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 9.30 MB

english, 2018

25

Potentials of CRISPR in liver research and therapy

Loesch, Robin, Desbois-Mouthon, Christèle, Colnot, Sabine

Journal:

Clinics and Research in Hepatology and Gastroenterology

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

26

Syndromes d’insulino-resistance majeure : clinique et physiopathologie

Vigouroux, Corinne, Magré, Jocelyne, Desbois-Mouthon, Christèle, Lascols, Olivier, Cherqui, Gisèle, Caron, Martine, Capeau, Jacqueline

Journal:

Journal de la Société de Biologie

Year:

2001

File:

PDF, 2.42 MB

2001

27

Non-coding RNAs open a new chapter in liver cancer treatment

Gougelet, Angélique, Desbois-Mouthon, Christèle

Journal:

Clinics and Research in Hepatology and Gastroenterology

Year:

2019

Language:

english

File:

PDF, 1.35 MB

english, 2019

28

High IGF1R protein expression correlates with disease-free survival of patients with stage III colon cancer

Zaanan, Aziz, Calmel, Claire, Henriques, Julie, Svrcek, Magali, Blons, Hélène, Desbois-Mouthon, Christèle, Merabtene, Fatiha, Goumard, Claire, Parc, Yann, Gayet, Brice, Taieb, Julien, Validire, Pierre

Journal:

Cellular Oncology

Year:

2019

File:

PDF, 651 KB

2019